Transcranial Photobiomodulation - Vielight Inc - Deutsch https://www.vielight.com/de/category/photobiomodulation/transcranial-photobiomodulation/ Fortschritte in der Photobiomodulationstechnologie und forschung. Sat, 27 Aug 2022 12:52:47 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.3 https://www.vielight.com/de/wp-content/uploads/2023/07/cropped-Vielight-Favicon-General-1-32x32.png Transcranial Photobiomodulation - Vielight Inc - Deutsch https://www.vielight.com/de/category/photobiomodulation/transcranial-photobiomodulation/ 32 32 Shedding Light on Photobiomodulation in Neuropsychiatric Disorders https://www.vielight.com/de/photobiomodulation-psychiatry/?utm_source=rss&utm_medium=rss&utm_campaign=photobiomodulation-psychiatry Thu, 14 Apr 2022 19:52:29 +0000 https://www.vielight.com/de//?p=23474 Over the last decade, there has been an increasingly positive shift in how transcranial photobiomodulation (tPBM) is viewed by mainstream medical science. If you’d like an in-depth overview of the potential applications of transcranial brain photobiomodulation in the field of psychiatry, this presentation by Dr. Corinne Fischer is for you: https://youtu.be/_WrocJ-rhfc Dr. Fischer is a [...]

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Over the last decade, there has been an increasingly positive shift in how transcranial photobiomodulation (tPBM) is viewed by mainstream medical science.
If you’d like an in-depth overview of the potential applications of transcranial brain photobiomodulation in the field of psychiatry, this presentation by Dr. Corinne Fischer is for you:

Dr. Fischer is a professor of Psychiatry at the University of Toronto and Director of Geriatric Psychiatry at St. Michael’s Hospital.
She touches on a few different topics, including Vielight technology:
• A conceptual overview of photobiomodulation in comparison to other neuromodulatory therapies.
• An overview of the basic science, anecdotal and clinical trial evidence for photobiomodulation in Alzheimer’s disease.
• An overview of potential applicability to other neuropsychiatric disorders.
Dr. Fischer is also the chief Principal Investigator for Vielight’s pivotal clinical trial for Alzheimer’s disease (228 participants): https://clinicaltrials.gov/ct2/show/NCT03484143
Vielight is proud to be a part of this change, contributing to faster advancement and, ultimately, acceptance of tPBM as a viable and effective non-invasive brain stimulation modality for numerous applications.

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Brain Waves and Their Usefulness https://www.vielight.com/de/brain-waves-and-their-usefulness/?utm_source=rss&utm_medium=rss&utm_campaign=brain-waves-and-their-usefulness Thu, 03 Mar 2022 20:10:07 +0000 https://www.vielight.com/de//?p=22744 Introduction At Vielight, we work tirelessly to offer products that are helpful to improve brain functions. A large part of this relates to the use of photobiomodulation (PBM) to modulate brain waveforms. Here we share why this understanding is useful, starting with the neurofeedback practitioners’ perspective. Neurofeedback training and the brain  Every brain is unique. [...]

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Introduction

At Vielight, we work tirelessly to offer products that are helpful to improve brain functions. A large part of this relates to the use of photobiomodulation (PBM) to modulate brain waveforms. Here we share why this understanding is useful, starting with the neurofeedback practitioners’ perspective.


Neurofeedback training and the brain 

Every brain is unique. Neurofeedback practitioners know that our brains respond to external stimuli in a variety of ways. These sensory stimuli can be helpful in modifying the brain’s responses when those responses are abnormal.

Neurofeedback training is based the principle that the brain uses sensory inputs to learn. Repeated information patterns indicate to your brain how to best prioritize received information. They also teach the brain response strategies to help it to interact most effectively with its immediate environment.

During a neurofeedback session your brain will receive cues based on changes in its attention and arousal. After some repetition, your brain learns which cortical behaviors have greater impacts on auditory or visual feedback patterns. As it learns, the brain begins to generate more of those desired responses and behaviors. Instead of traditional psychological “stick and carrot” techniques, neurofeedback targets the brain directly by employing various forms of stimulation.

Furthermore, neurofeedback training helps to train the brain to react differently to a stimulus or a set of stimuli in order to change an individual’s reaction. Brain wave frequencies, or neural oscillations, can play important roles in this process because they are present during specific brain states.

 

Brain oscillations, neurofeedback training, and photobiomodulation

Neural oscillations and brain states

Every brain state is associated with a particular band of brain frequencies, or rhythms. These rhythms are called “neural oscillations” because they are created by a multitude of neurons communicating with each other. These neural oscillations or brain waves can be registered and measured using an electroencephalogram, or EEG.

There is a correlation between a brain state and the type and frequency of neural oscillations produced during this state. It is possible that by stimulating a particular brain wave frequency, brain activity associated with this frequency can be modulated. Research shows that transcranial photobiomodulation (tPBM) can be effective in stimulating and modulating the brain.

Interventional and non-interventional ways to affect brain oscillations

EEG is an important part in neurofeedback training. It is a useful, non-interventional method of capturing brain state data and allowing for its analysis. In addition to non-interventional tools like EEG, the neurofeedback training also requires interventional tools. Brain photobiomodulation is one such interventional tool offering a non-invasive form of brain stimulation and modulation using light energy.

While brain PBM can start a restorative biochemical reaction in the neurons, it can also affect the brain’s natural oscillations. It can help to increase or decrease these oscillations, stimulating the brain to change its response. To achieve this goal, the light that is emitted during a tPBM session is pulsed at a specific frequency that is similar to natural brain oscillations. The choice of the pulse rate depends on the issue at hand and on the desired outcome.

A neurofeedback specialist uses equipment to map brain frequencies with qEEG, or quantitative electroencephalogram. Such frequency mapping can be helpful in assessing some deficiencies and abnormalities in the brain’s responses. Furthermore, the brain frequency mapping provides an image of brain oscillations and their respective frequency bands. These brain wave bands are defined differently by different contributors to the field. However, they are most commonly classified into the following five frequency band categories: delta, theta, alpha, beta, and gamma.

 

What are unique brain wave frequencies?

Brain’s delta wave frequency band — 0.1 Hz to 4 Hz 

delta brain waves or delta neural oscillationsDelta frequencies fall in the range of around 0.1 Hz to 4 Hz, and constitute the lowest range of brain frequencies. Brain activity in this frequency range correlates with the states of deep sleep, along with some anomalous processes.

In addition to being present in stages 3 and 4 of sleep, delta frequencies are also commonly predominant in infants under one year. The delta waves are the slowest and have the highest amplitude. They help the brain to focus inwardly, while decreasing awareness of the outside environment. These waves are helpful in attaining a state of connection with the unconscious mind.

High-performing individuals are able to decrease their delta waves to attain top levels of performance. On the other hand, individuals who are unable to decrease their delta wave activity in the brain can experience difficulty focusing. For example, individuals with attention deficit disorder (ADD) usually experience elevated delta wave activity when attempting to focus. Therefore, individuals with ADD have limited ability to stay focused and pay attention. This inability to focus can occur in anyone who has abnormal and unsuppressed delta wave reactions.

The inability to regulate delta wave activity impedes an individual’s ability to react fast to external stimuli. It can also be the cause of an inability to navigate the outside world with ease.

Brain’s theta wave frequency band — 4 Hz to 8 Hz 

theta brain waves or theta neural oscillations

Brain oscillations in the theta waves frequency band fall between approximately 4 Hz and 8 Hz. The brain activity in this frequency range often correlates with creativity, emotions, and sensations. Theta brain frequencies are present during inwardly focused brain activity, as well as the transitional state between alertness and sleep. Theta oscillations are often prominent during states of creative activities, meditation, and spiritual contemplation.

Furthermore, activity in the theta range correlates with states of learning and memory creation and integration. It can also be present during anxious episodes.

In comparison with delta waves, theta waves are faster. However, despite representing faster brain activity, they are also present during sleep. Theta wave activity commonly correlates with distracted or dreamy states and experiences.

Brain’s alpha wave frequency band — 8 Hz to 12 Hz 

alpha brain waves or alpha neural oscillations

Brain oscillations in the alpha wave frequency band fall between approximately 8 Hz and 12 Hz. Alpha wave activity correlates with states that combine relaxation, alertness, and awareness. For example, the brain’s alpha wave activity is present during some stages of meditation. Alpha band activity is also associated with mental resourcefulness, while enhancing a general sense of relaxation.

During alpha wave activity, individuals can accomplish a variety of tasks more efficiently. Alpha brain oscillations promote a sense of calm, allowing the brain to prioritize and to focus better. They are also commonly present in normal adults and teenagers in relaxed states. Alpha wave activity also correlates with a state of alertness, but it is absent when the brain is performing specific tasks.

Furthermore, the brain’s alpha oscillations are present during relaxed learning and while applying knowledge. They occur in both classroom and work environments.

It is possible to increase your brain’s alpha activity by doing deep breathing exercises, or simply by closing your eyes. If you wish to lower your alpha state, you could try doing a complex task, like a mathematical calculation. Alpha wave activity promotes the ability to easily switch between tasks while increasing inner awareness, balance, and calmness. It correlates with faster brain activity than that of delta and theta brain waves. Faster brain wave activity refers to activities in the states of alertness and the execution of cognitive tasks. Slow brain wave activity is present during dream-like and meditative states.

Brain’s beta wave frequency band — 13 Hz to 35 Hz 

beta brain waves or beta neural oscillations

Beta frequencies produce faster brain activity than alpha frequencies. Beta frequencies begin at about 13 Hz. This faster frequency occurs during a state of alertness and consciousness. If you are performing an analytical task with your eyes open, your brain’s beta oscillations are at work. This happens because communication among the neurons is increasing.

In general, when you are processing information about the world, beta wave activity is evident in the brain. This activity is present during various tasks ranging from mathematical problem solving to decision making.

Furthermore, because of its significant range, the beta frequency band consists of three sub-ranges — low beta, mid beta, and high beta.

Low Beta Frequency Band — 13 Hz to 15 Hz
The low beta frequency range activity is associated with a more relaxed and focused state.

Mid Beta Frequency Band — 15 Hz to 18 Hz
The mid beta frequency range activity is associated with alertness, mental activity, and focus.

High Beta Frequency Band — 18 Hz to 35 Hz
The high beta frequency range activity is associated with higher levels of alertness and even agitation.

Brain’s gamma wave frequency band — 35 Hz to 100 Hz 

gamma brain waves or gamma neural oscillations

The fastest of the five frequency bands is the gamma frequency. It is prominent when the brain is processing complex information that requires input from different parts of the brain. Intense thinking and problem solving are states that correlate with gamma wave activity. The brain oscillations in the gamma wave frequency band fall between approximately 35 Hz and 100 Hz.

Brain activity associated with a frequency of 40 Hz is of particular importance. The 40 Hz gamma wave activity is, presumably, present and needed for consolidation and complex processing of information from different parts of the brain. Whereas activity in this frequency range correlates with good memory performance, its deficiency correlates with learning issues and even disabilities.

 

Using photobiomodulation to modulate brain waves 

Considering the importance of brain oscillations, Vielight offers several products that have been found to modulate brain waves using photobiomodulation. The Vielight Neuro Alpha device trains the brain for mainly alpha brain waveforms and improves basic brain network functions. The Neuro Gamma elevates the faster brain waves of beta and gamma, and downregulates the slower delta and theta waves. The new Vielight Neuro Pro device offers the versatility of delivering PBM in the range from 0 to 10,000 Hz.

Understanding the effects of brain oscillations can be helpful in analyzing, supporting, and improving brain wellness. As studies suggest, brain PBM is a non-invasive form of neurostimulation that can help to affect and modulate brain oscillations. PBM with light pulsing at specific frequencies can help modulate and normalize brain oscillations. Considering that brain oscillations represent neural activity, this means that brain PBM can affect neural activity.

brain states and colors

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Understanding the Vielight Neuro 3 https://www.vielight.com/de/understanding-the-vielight-neuro/?utm_source=rss&utm_medium=rss&utm_campaign=understanding-the-vielight-neuro Tue, 25 Jan 2022 13:21:51 +0000 https://www.vielight.com/de//?p=22013 Mehr als ein halbes Jahrzehnt ist vergangen, seit wir den ersten Vielight Neuro auf den Markt gebracht haben, und es ist an der Zeit, die Gründe für sein Design zu überprüfen und zu bekräftigen. Als Pioniere der transkraniell-intranasalen Hirnphotobiomodulationstechnologie gibt es mehrere wichtige Gründe, warum unser neuestes Modell, das Vielight Neuro 3, in der [...]

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Mehr als ein halbes Jahrzehnt ist vergangen, seit wir den ersten Vielight Neuro auf den Markt gebracht haben, und es ist an der Zeit, die Gründe für sein Design zu überprüfen und zu bekräftigen. Als Pioniere der transkraniell-intranasalen Hirnphotobiomodulationstechnologie gibt es mehrere wichtige Gründe, warum unser neuestes Modell, das Vielight Neuro 3, in der Lage ist, auch in absehbarer Zukunft die höchste Wirksamkeit in Verbindung mit einem benutzerfreundlichen Design zu einem erschwinglichen Preis zu bieten.


Der intranasale Vorteil

“Warum die Nase?” – Diesen Satz haben wir schon viel zu oft gehört.

Wir haben die Nase wegen ihrer Lage und Struktur ausgewählt. Die Nase ist ein Einfallstor für die 810nm-Lichtenergie im nahen Infrarot (NIR), um den ventralen Bereich (Unterseite) des Gehirns zu erreichen, der sonst unzugänglich wäre. Die Regionen des Gehirns, die sich auf der Unterseite des Gehirns befinden, spielen eine wichtige Rolle bei emotionalen Reaktionen, Entscheidungsfindung und Selbstkontrolle. Darüber hinaus ist der nasale (olfaktorische) Bereich direkt mit der Gedächtnisverarbeitung (Hippocampus, entorhinaler Kortex) und der Emotionssteuerung (Amygdala) verbunden und ermöglicht den Zugang zu anderen Bereichen des Gehirns (Thalamus).


Die Wahl: Vielight Neuro Headset oder wiederverwendete Helme?

Es mag verlockend sein, einen Fahrradhelm, einen Hut oder einen Eimer zu nehmen, ihn mit LEDs zu bestücken und ihn ein “Photobiomodulationsgerät für das Gehirn” zu nennen.
Aber haben Sie schon einmal darüber nachgedacht, ob sie wirksam sind?

Nach einem Jahrzehnt Erfahrung als eines der ersten Unternehmen im Bereich der Photobiomodulation des Gehirns haben wir gelernt, dass eine effektive Photobiomodulation des Gehirns nicht so einfach ist. Vor allem, wenn wir ein Gerät anbieten wollen, das auf sichere Weise ein Maximum an Licht in das Gehirn leitet.

Als forschungsorientiertes Unternehmen haben wir festgestellt, dass bei der Maximierung der Wirksamkeit der Photobiomodulation des Gehirns mehrere Schlüsselfaktoren ins Spiel kommen.

     1. Übertragung von NIR-Lichtenergie

NIR-Lichtenergie ist eine Form der elektromagnetischen Strahlung, die aus Teilchen wie Photonen besteht, die wellenartige Eigenschaften haben.

In der Natur kann Lichtenergie die Zellphysiologie eines Organismus beeinflussen, aber wie bringen wir sie richtig an?

Mehrere Eigenschaften der Lichtenergie beeinflussen die Übertragung von NIR-Energie auf das Gehirn.

  • Die Lichtenergie wird bei der Ausbreitung über Entfernungen schwächer, weil die inverse square law of light.  
  • Lichtenergie wird vom Haar absorbiert.

Angesichts dieser beiden Faktoren sind Helme/Hüte usw. nicht ideal für die Photobiomodulation des Gehirns. Zusätzlich zu dem Energieverlust, der entsteht, wenn das Licht aus dem Helm/der Mütze/dem Hut usw. austritt, werden die Haare zu einer Hemmschwelle, da sie das Restlicht absorbieren, da die schwebenden LEDs keinen Kontakt mit der Haut haben.

Zweitens ist die Positionierung der LEDs für die Wirksamkeit entscheidend. Die LEDs müssen in den Bereichen des Gehirns positioniert werden, die am stärksten betroffen sind. Die Qualität der ausgewählten Stellen in Verbindung mit Leistung und Frequenz ist wichtiger als die bloße Anzahl der wahllos platzierten LEDs, die zu weit von der Kopfhaut entfernt sind.

Schlimmer noch, sie erzeugen und speichern unbrauchbare/unregulierte Wärme und beeinträchtigen den Komfort und die Tragbarkeit, da sie an Steckdosen angeschlossen werden müssen.

Und schließlich fehlt es den “Einheitsgrößen”-Designs an der Anpassungsfähigkeit an unterschiedliche Kopfgrößen. Igitt!

Geben Sie den Neuro

Figure 1. Penetration of NIR energy into a human cadaver using the Vielight Neuro.

Das Vielight Neuro ist für eine maximale Übertragung der Lichtenergie ausgelegt.

Das Headset der Neuro hat einen angeborenen Designvorteil, da die LED-Module der Neuro so konzipiert wurden, dass sie den Kontakt mit der Kopfhaut maximieren. Die mikrochip-gesteuerten LED-Module kontrollieren auch die Wärmeleistung,

Außerdem ist das Neuro-Headset so konzipiert, dass es sich an verschiedene Kopfgrößen und -formen anpassen lässt. Komfort und Effektivität für Ihr wichtigstes Organ – Ihr Gehirn.

     2. LED-Technologie

Ein berühmter Küchenchef sagte einmal: “Es ist ganz einfach: Gute Zutaten ergeben ein gutes Essen. Eine weitere wichtige Zutat (oder ein Faktor) bei der Photobiomodulation des Gehirns ist die Art der verwendeten LED-Technologie. Das Vielight Neuro verwendet mikrochip-geregelte LED-Dioden, die die gewünschte Leistung bei vernachlässigbarer Wärme erzeugen. Dadurch können die LEDs in direktem Kontakt mit der Kopfhautoberfläche stehen, um die Energieübertragung und -durchdringung zu maximieren.

Andererseits ist die Verwendung zahlreicher minderwertiger LEDs kein “Rezept für eine Katastrophe”, sondern für einen Misserfolg, da sie das Fehlen einer Wärmeregulierungstechnologie häufig durch eine geringere Leistungsdichte kompensieren. Bei Vielight kann unsere proprietäre LED-Technologie so viel Energie wie nötig innerhalb sicherer und effizienter Grenzen extrahieren.

     3. Sind mehr LEDs besser?

Nicht unbedingt – erstens müssen die LEDs genügend Energie mit der richtigen Wellenlänge erzeugen, um den Schädel zu durchdringen. Es ist wenig sinnvoll, eine hohe Gesamtleistung zu erzeugen, wenn nichts davon das Gehirn erreicht.

Als Verbraucher sollten Sie sich immer über den Unterschied zwischen Leistungsdichte (mW/cm2) und Gesamtleistung (mW) im Klaren sein. Die Leistungsdichte ist wichtig, nicht die Gesamtleistungsabgabe. Leistungsdichte und Wellenlänge (810 nm) sind die beiden wichtigsten Faktoren, die bestimmen, ob Photonen den Schädel durchdringen und das Gehirn erreichen. Die Gesamtausgangsleistung kann eine irreführende Angabe sein, da sie leicht durch die Verwendung vieler LEDs mit geringer Leistung und schlechter Qualität erreicht werden kann.

Das Sprichwort “Qualität vor Quantität” trifft hier zu!


Ausrichtung auf das Standardmodusnetz

There are approximately 86 billion neurons in the human brain. That’s a lot of neurons. For reference, there are approximately 200-400 billon stars in our galaxy.  Neurons are highly interconnected – our brain stimulation optimization theory is to pick the most important regions that show the highest interconnectivity. Hence, our research team chose the default mode network (DMN) as the primary target for the Vielight Neuro. Here’s why.

The Vielight Neuro targets the Default Mode Network.

  • Why the Default Mode Network?

The general health of the brain is often associated with the health of the default mode network (DMN), often considered the template network of the brain. It is a large-scale brain network primarily composed of the lateral parietal cortex, posterior cingulate cortex, medial prefrontal cortexprecuneus and the entorhinal cortex. The DMN is prominent when the brain is in its quiet state of repose.[1] Several brain diseases, including Alzheimer’s Disease and Parkinson’s Disease has been associated with dysfunctional DMN.[2]

In a nutshell, the Default Mode Network (DMN) has been linked to the general health of the brain and is involved in various domains of cognitive and social processing. Do you know of a better target for brain photobiomodulation? If so, let us know.


The Theory behind Pulse Rates

We have found that the pulse rate matters in brain PBM. The brain responds to pulse rate stimulation in specific ways. When we stimulate a healthy brain in gamma (40 Hz), we can elevate the amplitude of gamma and other fast waves in alpha and beta in the brain while reducing those of the slow delta and theta [3]. Independent researchers have found success in the use of the Vielight Neuro Gamma for dementia [4] , Parkinson’s Disease [5] ; and the Vielight Alpha (10 Hz) in traumatic brain injury [6] . However, please note that our devices are still general wellness device and not medical devices. We don’t claim efficacy for any indication and can only point towards research already published with our devices. (https://www.vielight.com/de//research)


Validation via Research

At Vielight, research is in our DNA. We understand the need to validate the engineering theory behind our devices with scientific data. A simple idea like placing LEDs on your head can turn surprisingly complex when taking different parameters into account, like the pulse rate, wavelength and power density to maximize efficacy.

With that in mind, we’ve invested heavily in research and clinical trials over the years. In fact, Vielight devices have the most published research in the field of brain photobiomodulation to date.

For a full list of published research that used our devices: Link

We’re grateful to all the research institutions we’ve collaborated with over the years and look forward to a bright future of discoveries together.


References

  1. Sormaz, Mladen; Murphy, Charlotte; Wang, Hao-Ting; Hymers, Mark; Karapanagiotidis, Theodoros; Poerio, Giulia; Margulies, Daniel S.; Jefferies, Elizabeth; Smallwood, Jonathan (2018). “Default mode network can support the level of detail in experience during active task states”
  2. Buckner, R. L.; Andrews-Hanna, J. R.; Schacter, D. L. (2008). “The Brain’s Default Network: Anatomy, Function, and Relevance to Disease”. Annals of the New York Academy of Sciences.
  3. Zomorrodi, R., Loheswaran, G., Pushparaj, A., & Lim, L. (2019). Pulsed Near Infrared Transcranial and Intranasal Photobiomodulation Significantly Modulates Neural Oscillations: a pilot exploratory study. Scientific Reports, 9.
  4. Chao LL. Effects of Home Photobiomodulation Treatments on Cognitive and Behavioral Function, Cerebral Perfusion, and Resting-State Functional Connectivity in Patients with Dementia: A Pilot Trial. Photobiomodul Photomed Laser Surg. 2019 Mar;37(3):133-141. doi: 10.1089/photob.2018.4555.
  5. Liebert A, Bicknell B, Laakso EL, Heller G, Jalilitabaei P, Tilley S, Mitrofanis J, Kiat H. Improvements in clinical signs of Parkinson’s disease using photobiomodulation: a prospective proof-of-concept study. BMC Neurol. 2021 Jul 2;21(1):256. Doi: 10.1186/s12883-021-02248-y.
  6. Chao LL, Barlow C, Karimpoor M, Lim L. Changes in Brain Function and Structure After Self-Administered Home Photobiomodulation Treatment in a Concussion Case. Front Neurol. 2020;11:952. Published 2020 Sep 8. doi:10.3389/fneur.2020.00952

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Combining Neurofeedback with Photobiomodulation https://www.vielight.com/de/combining-neurofeedback-with-photobiomodulation/?utm_source=rss&utm_medium=rss&utm_campaign=combining-neurofeedback-with-photobiomodulation Fri, 28 May 2021 20:40:47 +0000 https://www.vielight.com/de//?p=17032 What can be achieved by combining neurofeedback with photobiomodulation?   A creative and curious mind can be a beginning of something new, something important, even something big. This is as true in the field of arts as it is in the field of sciences. This article offers one more testament to these observations. Penijean Gracefire [...]

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What can be achieved by combining neurofeedback with photobiomodulation?

 

Penijean GracefireA creative and curious mind can be a beginning of something new, something important, even something big. This is as true in the field of arts as it is in the field of sciences. This article offers one more testament to these observations.

Penijean Gracefire is a licensed mental health counsellor (LMHC) in the state of Florida. She focuses on the applications of neurofeedback in her work with clients. Like many neurofeedback practitioners, she is excited by technology that can help her in her work. Unlike most, she is a techno geek, when it comes to her tools. Moreover, her interest in and fascination with technology helps her to discover new ways of helping her clients. She also happened to have an affinity for engineering and innovation, and pushes the frontier of her tools to the limits.

Thus, one day Penijean discovered trascranial photobiomodulation (tPBM) and Vielight’s tPBM devices. What happened when a talented neurofeedback practitioner with a curious mind decided on combining neurofeedback with photobiomodulation. Let’s find out the answer directly from Penijean Gracefire, LMHC.

How long have you been working with transcranial photobiomodulation (tPBM)?

Penijean: I’ve been interested in how light affects brains and bodies for as long as I can remember. Sometimes I joke that my interest in the therapeutic applications of light began when I was four years old. That is when I discovered that I could soothe a fussy younger sibling using a prism. Even as a child I noticed that my mood was affected by light and color, and I wanted to know why.

I picked up my first infrared light therapy device in 2005. Then I spent some years using tPBM for peripheral applications, such as relaxation and pain management.

What have brought you to tPBM initially and why did you stay with it?

Penijean: My initial experience using tPBM to stimulate the peripheral nervous system was informative and useful. However, I found that the applications were limited for my interests. Eventually I moved on to interventions that focused more on the central nervous system.

In 2017, I met Dr. Lew Lim at a neurofeedback conference. Our discussion of his Vielight Neuro device reignited my interest in tPBM. At that time I had been sitting on ideas for integrating infrared stim (stimulation) into a closed loop neuromodulation design. Dr. Lim was willing to allow me to use the Vielight platform to start creating new techniques. My design concept incorporated both the tPBM and the neurofeedback protocols.

The early results from the prototype designs were very promising. Thus, tPBM has become a much more central element in my protocol design process. I found it to be an excellent and naturally fitting complement to neurofeedback.

Where do you see synergies between tPBM and neurofeedback?

Penijean: Research indicates that tPBM has potential to support synaptogenesis – the creation of new synapses. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4870908/

Neurofeedback relies on brain plasticity (https://en.wikipedia.org/wiki/Neuroplasticity) to help individuals learn new ways to process information and regulate stress responses. Injury or illness can reduce neural capacity to adapt in real time to the changing demands of our environment. Brains need healthy and flexible neural networks to be able to prioritize and shift attention. Furthermore, they need to have the capacity to signal the central nervous system to wind down and relax. For example, this would be useful when a busy day is over.

Helping brains develop new connections, which support better function, is an important part of neurofeedback training. In my view, tPBM can potentially support the growth of those new pathways.

Combining tPBM with Neurofeedback, have you noticed anything new that could have a strong potential for helping your clients?

Penijean: The “feedback” part of neurofeedback means that we are giving the brain information based on its own behavioral changes. Typically, this feedback consists of musical sounds or visual data displays or, perhaps, an object that physically vibrates. For the feedback to work, it needs to be sufficiently novel and stimulating to recruit the brain’s attention.

After experimenting with and designing a number of innovative feedback techniques, I created the first EEG-modulated pEMF designs. While pEMF stands for pulsed electromagnetic field therapy, EEG stands for electroencephalogram. This protocol design has tremendous therapeutic potential. At the same time, these new integrated training protocols were yielding very exciting results. However, I work with many populations that are medically fragile and have compromised systems. Therefore, not all cases were suitable for the information-dense combination of neurofeedback and pEMF.

Combining Neurofeedback and Photobiomodulation

For some individuals, integrated tPBM and neurofeedback offers the perfect balance. Thus, on the one hand, this combination provides not so much feedback that their system feels overwhelmed. On the other hand, it provides not too little feedback that would fail to effectively recruit the brain’s attention.

I adapted my designs and created the first closed loop EEG-modulated pNIR (pulsed near-infrared light) protocols. This means that the individual not only simultaneously receives both the tPBM and the neurofeedback, but the NIR pulses themselves are changing in real time based on live EEG.

The combination of neurofeedback and tPBM is like a conversation with a wise friend while sitting in the afternoon sun. You receive both, the benefits of learning new helpful things about yourself and the benefits of absorbing natural light.

TPBM is the light source that supports your brain energetically, as it builds new connections. When this happens, the neurofeedback takes advantage of this optimized learning state to help your brain develop better cognitive function.

Can you provide some examples of how you employ tPBM in your neurofeedback practice?

Penijean: The practical flexibility of tPBM in a clinical setting is one of its strengths. Whether I use tPBM as a standalone therapeutic approach or combine it with other modalities often depends on individual needs.

Some people are sufficiently responsive. Thus, for them, 5-10 minutes of tPBM by itself is enough to produce a noticeable impact. Other people are a little more resilient. For those, I may do multiple things in a session, but in a sequence instead of simultaneously.

TPBM can be an effective primer at the beginning of a session before introducing sensory grounding techniques, or heart rate variability training. By applying tPBM to the head, we can help stimulate neural activity immediately prior to a neurofeedback session.

When combining tPBM with other modalities, you are only limited by your own creativity. Therefore, I try to be as creative as appropriate. For example, I may have someone wear a pair of violet eye lenses while receiving a 40hz tPBM stimulation. This helps to create a shift in gamma activity. I can also have someone wear a pair of dark amber or orange lenses, when receiving a 10hz stimulation. This can help to support slowing down into a more alpha-wave friendly state.

I noticed that layering other inputs over tPBM can also help with state flexibility and integration. Thus, utilizing inputs like binaural beats, vibrating sensory aids, or progressive relaxation audio can be helpful.

What benefits do you see tPBM on its own and in combination with neurofeedback can provide at this stage?

Penijean: A helpful way to think about these modalities is in terms of how much of a resource demand they place on a nervous system. This can be in terms of demand on attention, arousal, processing and integration. Each technique is a different way of asking the brain to prioritize and learn from specific types of sensory information. Penijean Gracefire with Vielight tPBM devicesFurthermore, different brains may respond differently to the stimuli.

Some brains learn more easily when we present information to them in simpler ways. Those people make quicker, more noticeable progress, if they receive tPBM and neurofeedback separately. This separation can be done either during different sessions, or at different times during a session.

Other brains have more capacity for integrating complex information. They seem to benefit more from the combination of neurofeedback and tPBM. Often such individuals are less medically fragile and have more physical resources to help them process more dense cognitive tasks.

Both of these approaches are beneficial. Usually, we start with the simpler approach and build up over time to more complex feedback designs.

What benefits do your clients report during and following your protocols that include tPBM?

Penijean: Clients report results across a wide spectrum. Some improvements are expected, such as better sleep, more functional attention and cognitive flexibility, and less anxiety. However, I am pleasantly surprised by how frequently clients report unanticipated benefits.

For example, one elderly woman recovered her ability to remember music that she thought she lost years ago. An executive who came to reduce his anxiety around work was very happy to discover his golf game improved significantly. Children, brought in by parents concerned about academic performance, have noticed improved visual integration, better frontal lobe inhibition, and increased social awareness. As you can see, there is a lot to learn.

As you are aware, Vielight has developed and will be launching a unique new tPBM device, the Neuro Pro. What do you think the applications of the Neuro Pro can be for neurofedback practitioners and their patients specifically?

Penijean: Being both a health and wellness practitioner and a designer of innovative ways to interact with the brain, I am limited only by two things. These things are my own creativity, and the capabilities of my tools. I am someone who tends to push devices to their limits. Therefore, I am always looking for user interfaces that allow as much customization and choice as the platform can support.

The Neuro Pro is the type of device, which will allow to design and build tPBM sessions specifically tailored to a specific individual. The capacity for programming a series of pulses based on a person’s unique EEG signatures will be unprecedented.

While not every practitioner will want to design their own protocols, the Neuro Pro will still provide the platform for all practitioners to run the protocols developed by researchers.

New Brain Modulation Techniques

When new effective brain modulation techniques emerge, they can only spread as widely as the availability of the technology. Neuro Pro will support the innovation of new tPBM protocols. At the same time it will provide the devices by which these protocols can be implemented and used.

This means that neurofeedback providers will be able to pair up more precise tPBM protocols with the customized EEG biofeedback. Techniques that have not been possible before, such as cross frequency coupling feedback timed synced with near infrared pulses, to improve neural networks, or ramping frequency delivery protocols that help the brain learn state flexibility, may become much more accessible.

What could be the applications of this device for researchers and health and wellness practitioners dealing with human brains?

ISNR 2021 Vielight AdPenijean: One of the critical principles of interacting with the brain in effective ways is being able to observe and, to a degree, mimic some of the complex dynamics, which make up flexible neural states. The brain habituates quickly to repetitive stimuli, because so it can prioritize its limited resources.

The Neuro Pro offers the possibility of building more sophisticated and precise tPBM protocols. These protocols could not only capture the brain’s attention better, but also could produce informational sequences, which more closely match neural patterns. Thus, this Vielight device opens potential for advanced stimulation designs that can target network behaviors with more nuance and specificity.

What else would you like to add in conclusion?

Penijean: In an increasingly tech savvy society, as we are suffering from the habitual overexposure to specific light frequencies from heavy screen use, it seems poetic to me that we may be able to help rewire these brains using other types of light. The light is information. Our bodies rely on light sources to help us regulate various systems and functions. Thus, regulating circadian rhythms, affecting our sleep cycles, our immune systems, our metabolism, and our mental health are some possibilities.

Wavelengths of light are a language. The more we learn, the better we can speak to our body in ways, which it recognizes as familiar and healing. Transcranial photobiomodulation could be an invaluable mechanism in our pursuit of improving brain’s function and wellbeing.

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Vielight PBM research and development efforts continue https://www.vielight.com/de/vielight-pbm-research-and-development-efforts-continue/?utm_source=rss&utm_medium=rss&utm_campaign=vielight-pbm-research-and-development-efforts-continue Thu, 27 May 2021 20:06:30 +0000 https://www.vielight.com/de//?p=17011 Vielight COVID-19 Clinical Trial Passes Interim Analysis and Continues to Recruit Subjects Please, spread the word to help us recruit more quickly! Many of you may be aware that last year Vielight Inc. launched a COVID-19 clinical trial in USA and Canada. This trial is intended to determine whether the home- use Vielight RX Plus [...]

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Vielight COVID-19 Clinical Trial Passes Interim Analysis and Continues to Recruit Subjects

Please, spread the word to help us recruit more quickly!

Many of you may be aware that last year Vielight Inc. launched a COVID-19 clinical trial in USA and Canada. This trial is intended to determine whether the home- use Vielight RX Plus helps to accelerate recovery. Positive data would suggest that the device helps take the load off the hospital system. This would also indicate that it is an effective and user-friendly way to recover from COVID-19. Importantly, it would be done within the confines of one’s familiar environment. The Vielight RX Plus photobiomodulation (PBM) device is designed to deliver near infrared (NIR) and red light to the infected areas of the body. It is intended to help the body by boosting its immune system, reducing inflammation and repairing damaged cells.

An interim data analysis was conducted for the Vielight COVID-19 clinical trial. It was done to determine if the early data justifies continuing the clinical trial or abandoning it for futility. The independent statisticians’ report supports the feasibility of the trial and its continuation to completion, with the potential for success.

Based on the encouraging interim results, Vielight Inc has been working tirelessly towards completing the study as soon as possible. However, we are in the final leg, the last obstacle being the shortage of about 20 qualified participants. To qualify for this trial, the person must have been formally diagnosed with COVID-19 in the last 10 days, must not require hospitalization and must be between 18 and 65 years old. More information is available at covidlightstudy.com, including compensation. Your help recruiting final participants for this study will be greatly appreciated. Kindly spread this information to your network.

Dr. Lew Lim Recognized in a Canadian Award for Innovation

Virtual ACCE Awards PresentationOn April 24, 2021, The Association of Canadian Chinese Entrepreneurs (ACCE) awarded Dr. Lew Lim, our founder & CEO, the Canadian Chinese Entrepreneur of the Year for 2020 & 2021 in the Most Innovative category. The selection committee recognized the uniqueness and innovation of Vielight technology, its impact on society and its vast future potential in helping people with their health needs at affordable prices. The rigorous selection was an outcome of an extensive due diligence review by members of an independent committee. The committee included senior members of a Canadian academic institution, the Federal government, a major international accounting firm, a major financial institution and the media.

Neuro Pro Progress Updates

The Neuro Pro is a major upgrade to and a departure in a new direction from the established Vielight Neuro Alpha and Gamma devices. It pushes the boundaries of the potential of brain PBM by offering the user the unprecedented ability to safely manipulate transcranial photobiomodulation (tPBM) parameters.

Compared to the existing Neuro models, the Neuro Pro offers extra LEDs for positioning on the dorsolateral prefrontal cortexes (DLPFC), which are associated with executive function and cognition. Among many other features, the pulse frequencies of the NIR LED modules can be set to a continuous wave or to pulse frequencies of up Vielight Neuro Pro tPBM systemto 10,000 Hz. The parameters are keyed in through an app on the accompanying smart phone that is specifically paired with the controller.

From Dr. Lew Lim

Dr. Lew Lim, the inventor of the Neuro Pro platform and Vielight products, notes: “My vision of the Neuro Pro is of a platform that provides its users a tool for safe experimentation to achieve new heights in brain states. The Neuro Pro was designed to be user-friendly and versatile with the creative and curious end-user in mind. Its novelty and versatility are unmatched by any other tPBM or brain stimulation device at any price.

Knowledge in neuroscience is helpful in exploiting the full capabilities of the Neuro Pro, but it is not a prerequisite for enjoying its capabilities. Through the simple sweeping of different frequencies, users can recognize sweet spots that could lead to better brain health and cognition. The changes and improvements are observable in QEEG readings, making the Neuro Pro a powerful adjunct for neurofeedback practitioners. Furthermore, advanced meditators who have tested the Neuro Pro report experiencing positive altered states during the testing of the early prototypes.”

Dr. Lim added, “It is in the culture of our team to continuously explore how we can help to improve human functions, particularly the brain. The Neuro Pro democratizes experimentation by individuals for personal mental improvements. The device has built-in safety features for certain key parameters, like power density, to ensure the safety of the user.

The sophisticated and yet user-friendly Neuro Pro system is supported by complex engineering. The team at Vielight and selected associates have been testing the prototypes rigorously to ensure that we have a quality product fully ready for release. We are also ensuring that the system is fully certified for safety. Considering the time needed to attain the high level of satisfaction associated with the Vielight devices, we expect to launch the Neuro Pro in the third or fourth quarter of 2021.”

Dr. Alison Smith to Present the Neuro Pro at ISNR 2021

Recognizing the very significant interest in the long-awaited Neuro Pro as a highly sophisticated brain stimulation platform, a live online presentation and Q&A session has been set aside at the ISNR Annual Conference. If you have registered or are considering attending the conference, please note that this informative session is scheduled for Friday, June 25 between 5:30 PM and 6:30 PM PDT. Access more ISNR 2021 Vielight Adinformation at the ISNR website by following this link.

Dr. Lew Lim to present at ISNR 2021 conference (June 25-27 2021)

Dr. Lew Lim will be speaking on “Treating COVID-19 with Photobiomodulation – Short-term Recovery and Long-haul Neuro-regulation” at the online ISNR conference, taking place from June 25 to 27, 2021. This session is scheduled for 7:00 AM PDT / 10:00 AM EDT on Saturday, June 26, 2021. During this presentation, Dr. Lim will share the science behind the ongoing pivotal clinical trial to validate the benefits, delivered via the Vielight RX Plus PBM device, as a treatment for COVID-19. Furthermore, he will also be sharing his knowledge on how PBM can potentially be used to treat “long haul” COVID sufferers. Access more information by following this link to the ISNR schedule.

Dr. Lim will also be conducting a 3-hour workshop on Sunday, June 27, 2021 at 2:30 PM PDT/5:30 PM EDT to 5:45 PM/8:45 PM EDT. The subject of this workshop will be “The Principles and Practice of Photobiomodulation Relevant to Neurofeedback Updated for 2021”. Practitioners and those with some understanding of neuroscience will find this highly educational. The updated information includes new discoveries that are useful and have not yet been made public. Dr. Lim will be sharing many tips on how to apply PBM to improve brain functions. Access more information by following this link to the ISNR workshops schedule.

Dr. Neda Rashidi joins Vielight

Vielight welcomes Dr. Neda Rashidi into its research team. Dr. Rashidi is a medical doctor educated at the University of Tehran. She obtained a Master in neuroscience from Trento University in Italy and is now completing her PhD at the University of Toronto in Canada. Apart from her medical degrees, she is skilled in neurophysiology and neuroimaging.

Peter Kusiak joins Vielight

Vielight welcomes Peter Kusiak as its Data Analytics Developer and Acting Quality Manager. Peter brings with him capabilities in artificial intelligence, as well as experience in quality management systems. He obtained a BSc in Psychology from the University of Toronto, and a Graduate Certificate in Artificial Intelligence Analysis, Design, and Implementation from Durham College, Canada.

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Case Study: Vielight Neuro Helps Regrowing Human Brain Cells https://www.vielight.com/de/vielight-neuro-helps-regrowing-human-brain-cells/?utm_source=rss&utm_medium=rss&utm_campaign=vielight-neuro-helps-regrowing-human-brain-cells Thu, 15 Oct 2020 15:45:28 +0000 https://www.vielight.com/de//?p=14676 Landmark Brain Injury Case Report   The loss of brain cells from brain injuries is a well-documented phenomenon. In moderate to severe cases of brain injuries, the generalized loss could amount to 5% of brain cells per year. These are cells that include those in the areas of the brain that affect cognition and memory functions. [...]

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Landmark Brain Injury Case Report  

MRI brain baseline Chao study 2020The loss of brain cells from brain injuries is a well-documented phenomenon. In moderate to severe cases of brain injuries, the generalized loss could amount to 5% of brain cells per year. These are cells that include those in the areas of the brain that affect cognition and memory functions. In a recent study, a professional hockey player, with multiple concussions and generalized loss or atrophy of the brain cells, was observed. These deficiencies were the results of injuries received during his hockey career. Professor Linda Chao of the University of California San Francisco (UCSF) was the lead investigator in the study. The subject was treated with two Vielight transcranial-intranasal devices — the Neuro Gamma, followed by the Neuro Alpha, over a period of eight weeks.

The results of this study showed improvements in learning, memory, executive functions, attention, and mental processing speed. This is a very significant finding because, for the first time ever, a study was able to show measurable growth of gray matter due to transcranial photobiomodulation (tPBM), in some important areas of the brain, in a human. The growth was present in the hippocampus and thalamic areas.

Indeed, the study provides significant evidence that PBM helps the brain to repair itself!  Magnetic resonance imaging (MRI) was used to measure the growth of neurons. In addition to growth and repair of damage in the brain cells, the brain was observed to perform more efficiently.

The study was published in the September issue of Frontiers in Neurology. This is a link to the study: https://www.frontiersin.org/articles/10.3389/fneur.2020.00952/full

Dr Lew Lim Comments

Co-author Dr. Lew Lim, who is Vielight Founder & CEO, commented, “For objective evidence of real recovery in a brain, the gold standard is a measured increase in the volume of brain cells through objective imaging. Although this is only a single case, the evidence could be stronger than in a controlled study with several subjects. This is because there are no placebo-related false positives in such brain imaging. The finding also gives us more optimism for our ongoing pivotal clinical trial for Alzheimer’s, where the reversal of brain atrophy would contribute to positive outcomes.”

More information about the Alzheimer’s pivotal clinical trial can be found by following this link: https://www.vielight.com/de//vielight-alzheimers-disease-trial/.

Dr. Lim added, “These findings provide an additional validation of earlier studies that presented improved brain functions, when
subjects with traumatic brain injuries were treated with a Vielight Neuro or other PBM-based brain treatment methods. I look forward to more evidence and validation through future studies involving more subjects, which employ brain imaging methods, including EEG.” 

We are Actively Recruiting for the COVID-19 Clinical Trial

Our clinical trial, to indicate the Vielight RX Plus for COVID-19, is ongoing. We are actively recruiting subjects to evaluate whether our device could be a first-line treatment, and helpful in offering a solution to this great COVID-19 pandemic.

The study collects data for evidence to confirm whether a person infected with COVID-19 recovers more quickly when treated with a Vielight RX Plus device.

It would be a welcome alternative to those who prefer a non-pharmaceutical treatment. 

Please help to pass the word around that we are recruiting subjects who have been tested and confirmed to have COVID-19 in Ontario, Canada and throughout the US, particularly in the states of Florida and Texas.

More information about the trial is accessible at https://covidlight.ca.

Vielight and the Clinical Trial for COVID-19 Covered in the Canadian National News

One of Canada’s largest television networks, CTV, featured Vielight’s COVID clinical trial in a national news segment. A recording of this segment, “Scientists studying whether light can be harnessed to kill the coronavirus”, is available at https://www.ctvnews.ca/health/coronavirus/scientists-studying-whether-light-can-be-harnessed-to-kill-the-coronavirus-1.5141292.

Among the interviewed was Guillermo Tearney, co-director of the Massachusetts General Brigham Center for COVID Innovation. He supports the premise that light therapy can cause sick and dying cells to heal and recover. As earlier studies suggest, the red and near infrared (NIR) light can reduce the viral population, diminishing the severity of effects of COVID.

The principal clinical trial investigator of the Vielight trial, Dr. Roy Tingley, and retired Associate Prof. of Harvard Medical School, Michael Hamblin, were also interviewed.

Dr. Lew Lim to Present at Special Neurofeedback Webinar

On Wednesday, October 21, 2020 at 12 PM EST, Dr Lew Lim will present a webinar, “What Neurofeedback Practitioners Need to Know about Photobiomodulation”.

what neurofeedback practitioners need to know about PBMThe webinar description states that, “Neurofeedback practitioners increasingly recognize that photobiomodulation (PBM) can produce significantly positive outcomes when light energy is directed to the brain in calculated doses. However, it is an emerging application that clearly has not revealed all of its secrets — in fact far from it. Probably, few are better positioned to discuss newly discovered evidence as well as ongoing research than Dr. Lim. He is supported by his large team of researchers and by a network of third-party researchers.

The webinar will cover some biological mechanisms that are key to understanding the differences between PBM and other forms of brain stimulation, the effect of dose, pulsing and focal stimulation. This one-of-its-kind seminar covers the areas of investigation into enhancement of the effectiveness of PBM and the vast potential of its use, awaiting to be discovered. Topics like cognition, altered states, pain relief, as well as ongoing medical clinical trials, will be discussed. We expect that with more investigations and studies, there will be startling impact on the future of brain stimulation.”

This webinar is open to anyone with an interest in the latest understanding of the parameters for effective brain PBM. It can be of particular interest to those seeking the latest information on how to improve one’s brain functions. Registration information is available at https://isnr.org/events/what-neurofeedback-practitioners-need-to-know-about-photobiomodulation-presented-by-dr-lew-lim.

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Brain Stimulation Devices Boosting General Wellness https://www.vielight.com/de/brain-stimulation-devices-boosting-general-wellness/?utm_source=rss&utm_medium=rss&utm_campaign=brain-stimulation-devices-boosting-general-wellness Mon, 17 Aug 2020 18:31:49 +0000 https://www.vielight.com/de//?p=14178 General wellness devices come in many forms and colours. Some sleek, some quirky-looking, they are useful gadgets, which can be helpful for your wellbeing. Brain stimulation and neural modulation are only two of the areas where new generations of general wellness devices are gaining footprint. Only a few years ago brain stimulation was a closed [...]

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General wellness devices come in many forms and colours. Some sleek, some quirky-looking, they are useful gadgets, which can be helpful for your wellbeing. Brain stimulation and neural modulation are only two of the areas where new generations of general wellness devices are gaining footprint.

Only a few years ago brain stimulation was a closed playground. It was destined for cutting edge science and research. However, today, general wellness devices can stimulate your brain and help to boost your mental acuity right at your home.

Brain wellness is garnering a lot of attention over the recent decade. Even younger adults, those under forty, are interested in supporting their brain. This interest is not without bases. Thus, statistical data is painting an unpleasant picture that shows proliferation of dementia in our society. That is a strong enough stimulus for fear to trigger a sympathetic response in the brain. Truly, the perspective of suffering through dementia is not a particularly appealing scenario for anyone. No wonder people are searching for ways to support and help their brain.

Brain Stimulation Devices

brain stimulation wellness devicesAmong options available to support brain wellness, brain stimulation devices are the newest category of products. Some of them are medical devices and some are general wellness devices. The latter category intended to help in supporting brain wellness. Let’s dig in deeper.

Even for those with highly consumerist attitudes and high expectations it can be hard to imagine that a small and strange-looking contraption can stimulate the brain. Furthermore, the new technology pushes this category of device even further, and some brain stimulation devices can do their job anywhere. Thus, no need to go to a specialized laboratory or some other dedicated facility.

For example, you can simply pop the device on your head, press a button, and off goes a brain stimulation session. Moreover, no drilling required, so the number of holes in your body will not increase. You can also preserve your lovely skull in its original shape, which is likely an important factor for many.

Funny things aside, the fact that today anyone can purchase an at-home-use brain stimulation device has to be awe-inspiring. A specialized consumer device that can deliver neural stimulation in an unsupervised, self-administered session is worth appreciation and continued research. That is exactly what Vielight and many researchers do.

Are Vielight Brain Modulation Devices Safe

Furthermore, speaking about such devices, it is important to note that Vielight is a leading designer and manufacturer of brain stimulation devices. The Vielight devices utilize near infrared light (NIR) to reach and stimulate the brain transcranially.

Not less important is the fact that this form of neural stimulation, photoneuromodulation (PNM) or transcranial photobimodulation (tPBM), is noninvasive. Moreover, it is likely the least invasive form of neural stimulation. Therefore, the Vielight brain stimulation devices are not only simple in exploitation, but also safe and noninvasive consumer-focused products.

Neural Stimulation vs Brain Stimulation vs Brain Modulation

Do you find some of the terminology around brain stimulation to be confusing? Sometimes you can hear or read terms neural stimulation, sometimes, brain stimulation, brain modulation and sometimes, transcranial photobiomodulation. Although these terms may sound somewhat different, in general, they refer to similar processes, and some use them interchangeably. For example, transcranial photobiomodulation (tPBM) is a form of brain stimulation. On the other hand, neural stimulation can be used completely interchangeably with brain stimulation and means exactly the same.

However, brain modulation has somewhat different connotations. Unlike the other terms, it implies the process of changes to the brain, and not just its stimulation. Thus, Vielight tPBM devices do both, brain stimulation and brain modulation.

Neural Stimulation and Brain Wellness

At this point you might have questions about how brain stimulation translates into brain wellness. A simple answer is stimulation presumes that something will happen to change the status quo, or the current state of something. In this case the brain is the subject of change.

For example, some of you may have experienced slower reaction and some sort of decline in mental focus. Such changes could happen because some of the neurons may become hypoxic over time. There can be a number of reasons for such changes. Natural aging of the brain is one of them.

When this happens, your neural networks may not function as well as they once where. In this case, the focus of brain stimulation could be on improving mental acuity. Thus, a tPBM device could help to stimulate the neurons in the brain. Following stimulation, some of the hypoxic neurons could become more active. They can start firing again and participating in the creation of stronger neural networks. Consequently, this type of brain stimulation can provide support for the brain. It can also lead to improvements in mental acuity and overall brain wellness.

Non-medical Brain Stimulation

However, it is important to note that this form of brain stimulation in not medical. This means that it is not intended to cure an illness or its specific symptoms. On the other hand, the goal is to provide support for the brain, improve mental acuity and to delay brain’s aging.

The devices that can offer such stimulation fall in the category of general wellness devices. These are not medical devices. Of course, there are other forms of brain stimulation and neural modulation. Some of them can support general brain wellness, others have medical use, yet there are those that can do both. However, that would be a subject for another article.

At-home Brain Modulation 

As you may recall from the above, a big thing about modern brain stimulation devices is their simplicity of use. On the one hand, new technology is very sophisticated. On the other, it allows to simplify many functions. It is also conducive of compact product designs, which can comfortably fit with any settings of a personal dwelling. After all, you would only need a small footprint to put the device on. It can be not much bigger than the size of a book. Furthermore, the latest brain stimulation devices can be also so simple in exploitation that anyone can use them at home.

For example, Vielight products are known for their simplicity and one-button-push operation. This is manageable even on the days when you are very tired or have little energy. No need to deal with complex contraptions or unruly technology. Instead, the Vielight device offer simple design and one button to press to start brain stimulation and neural modulation.

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Brain Stimulation with Light Energy https://www.vielight.com/de/brain-stimulation-using-light/?utm_source=rss&utm_medium=rss&utm_campaign=brain-stimulation-using-light Tue, 11 Feb 2020 15:03:58 +0000 https://www.vielight.com/de//?p=12237 Brain stimulation is a term that may sound both familiar and distant to many. What about the terms brain stimulation using light energy or non-invasive brain stimulation? How about transcranial photobiomodulation? Often enough you hear words that seem simple to understand, but, somehow, they create a fuzzy aura of vagueness and mystery. This is particularly [...]

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transcranial photobiomodulationBrain stimulation is a term that may sound both familiar and distant to many. What about the terms brain stimulation using light energy or non-invasive brain stimulation? How about transcranial photobiomodulation? Often enough you hear words that seem simple to understand, but, somehow, they create a fuzzy aura of vagueness and mystery. This is particularly common with subjects related to science. Avoiding that strange feeling of being “the stupid one” is something that everyone desires. Thus, before digging deeper into scientific, technical and beneficial aspects of brain stimulation, it appears important to clarify what exactly it is.

The words “brain” and “stimulation”, by themselves, are easily recognizable by most people. However, the combination of the two may cause a confusion in some. On its own the word “stimulation” refers to the action of improving performance of something or of someone. Combining the words “brain” and “stimulation” clearly references a process that encourages some transformation or modulation in brain activity.  The lack of clarity appears because there is no explicit reference to what exactly this “brain stimulation” is or does.

Context and Meaning of the Term Brain Stimulation

In the absence of a clear context, this subject can present numerous inferences. A more specific context would be helpful in better understanding the meaning of the term brain stimulation. In some cases, unfortunately, too often, terms like this one are thrown around without much clarity and specific context. In others, they represent a scientific or medical lingo, and can cause moments of intellectual discomfort to a layperson.

Thus, in reference to a healthy individual with no brain related abnormalities, the term “brain stimulation” can mean a few things. For example, maximization of this individual’s cognitive abilities through some form of brain stimulation is one, somewhat generic, option. By establishing these references, you can draw a more cohesive concept that is much easier to understand. Meanwhile, additional information, which can further clarify this concept and process, is still missing. For example, there is no specific reference to the form of stimulation, which is an important condition. There are numerous ways in which a brain can be stimulated, and some are more complex and invasive than others.

You are probably noticing how more contextual clarity can help to define and simplify your understanding of new complex terminology. Now that this matter is out of the way, let’s dive a little deeper into the subject of brain stimulation.

Types of Brain Stimulation Simplified

As often does any intellectually challenging material, brain stimulation requires clarification and even some simplification. Thus, it is easy to identify two general types of brain stimulation based on the levels of its intrusiveness. One is non-invasive brain stimulation (NIBS), and the other type would be invasive. Each of these types include various forms or modalities of brain stimulation. It most likely sounds to you that the non-invasive brain stimulation would be preferred over the invasive one. In principal, it would be the case, if all modalities of brain stimulation could deliver equal benefits. In reality, selection depends on a specific need at hand, and the capability of a given modality to achieve it.

Without getting deep into complex neurological and medical aspects of various form of brain stimulation, let’s discuss what they are.

Briefly About Non-invasive Brain Stimulation Terms

Non-invasive forms of brain stimulation are gaining attention from both the scientists and the practitioners alike. The more commonly used forms of non-invasive brain stimulation (NIBS) are Transcranial Magnetic Stimulation (TMS) and Transcranial Current Stimulation (TCS). However, one of the most recent forms of non-invasive brain stimulation is Transcranial Photobiomodulation (tPBM) or Transcranial Photoneuromodulation (tPNM). TPBM is rapidly evolving through growing research spurred by its simplicity, low cost and a potentially wide spectrum of applications.

Notably, the word “transcranial” is prominently present in the names of all three forms of non-invasive brain stimulation. Not to be confused with “intracranial” meaning “inside the skull”, transcranial means “passing through the skull”. In the case of non-invasive brain stimulation, the stimulation is delivered transcranially, or from outside of the skull. Such procedure does not require and physical alterations to the skull, neither outside, nor inside. Hence, the name of the procedure, non-invasive brain stimulation.

On the other hand, invasive forms of brain stimulation usually presuppose a direct stimulation of the brain inside the skull. Common techniques of invasive brain stimulation include Deep Brain Stimulation (DBS) and neurosurgical procedures. These techniques require direct intracranial access to the brain. In simple words, the skull has to be opened surgically in order to deliver stimulation to the brain.

Transcranial Photobiomodulation for Brain Stimulation

non-invasive brain stimulationAs new technologies evolve, new modalities for therapies emerge. Light therapy, or photobiomodulation (PBM), has been known and studied considerably for over half a century. Recently, a body of promising evidence has emerged from new research in support of the concept of transcranial photobiomodulation (tPBM). Research studies show that near infrared light (NIR) can penetrate the skull deep enough to reach the brain. Moreover, the studies also show that NIR can affect the brain in a number of meaningful ways.

Thus, the scientists observed that following tPBM sessions using a Vielight Neuro Gamma device, subjects presented increased interconnectivity between influential parts of the brain’s Default Mode Network (DMN). (L.L. Chao, 2019). DMN is an important cluster of brain regions responsible for the resting state of brain. Expressly, DMN enables brain activity during periods of rest, when you do not engage in any specific task. Furthermore, DMN engages in the social working memory (SWM). You use social working memory when you are navigating your social world. For example, SWM engages when you may think of friends, colleagues, others’ beliefs and other social paradigms. (M. Meyer & M. Lieberman, Social Working Memory: Neurocognitive Networks and Directions for Future Research, 2012).

Neurodegenerative disorders and transcranial photbiomodulation

The Dr. Chao finding is highly valuable for a number of reasons. One of them is the relationship between DMN functionality and Alzheimer’s Disease. Thus, functional connectivity in the DMN is disrupted in the brains of those suffering from Alzheimer Disease. The transcranial LED modules of the Vielight Neuro devices are specifically designed for placements that target the nodes of the DMN. This fact could potentially explain the increased functional connectivity in Alzheimer’s subjects observed by Dr. Chao.

When it comes to neurodegenerative conditions or an impairment in the brain, tPBM is showing promise. The range of research for applications of tPBM with NIR stimulation is increasing. Today it includes such complex neurodegenerative disorders like Alzheimer’s Disease and Parkinson’s Disease, as well as PTSD, stroke and depression. (Berman 2017).

Furthermore, a recently published exploratory study has shown more evidence of the positive effects from brain stimulation by transcranial photobiomodulation. (R. Zamorrodi et al, 2019). The subjects in this study were healthy individuals. It presents that even a single twenty-minute tPBM session, using a Vielight Neuro Gamma device, causes significant changes in brain oscillations.

What are brain oscillations?

Brain oscillations, or neural oscillations, are forms of repetitive electrical activity in the brain. They are considered important building blocks in sensory-cognitive processes. (E. Basar, Dialogues in Clinical Neuroscience, 2013). Moreover, brain oscillations are attributable to firings of neurons in the brain, and can vary in frequency, power and phase. These three parameters are measurable and linkable to certain brain states and activities. The insights from the above study can help to optimize tPBM parameters for brains. Optimization can be done for normal brains, those with neurological anomalies, like Alzheimer’s Disease, and those with trauma, like TBI.

Why Non-invasive brain stimulation (NIBS) using light is important?

The simpler way to respond to this question would be to base it on the benefits of the brain stimulation. Importantly, the fact that the therapy is non-invasive reduces the risks and increases the tolerability of the procedure. Therefore, NIBS using light opens another dimension in its non-invasive characteristics. The procedure becomes not only painless, but maybe even undetectable for those who undergo NIBS using light. In absence of acute sensitivities to light, or irritation by the foreign objects, most would sense only the physical pressure of the tPBM device.

Thus, the primary factors of importance of non-invasive brain stimulation using light, are the benefits that this photobiomodulation can deliver. The extent of these benefits is under the lens of a significant scientific research. A worldwide body of scientific evidence is growing to offer a better understanding of the effects of tPBM on the brain. As this new and exciting field of research is gaining momentum, so does the extent of tPBM applications and benefits. The future of non-invasive transcranial brain stimulation with light looks promising. Meanwhile, it awaits further validation and support from solid, evidence-based research. You can expect more news, as new research finds its way into reputable scientific publications.

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Vielight Research Grows https://www.vielight.com/de/vielight-research-grows/?utm_source=rss&utm_medium=rss&utm_campaign=vielight-research-grows Fri, 07 Feb 2020 14:57:33 +0000 https://www.vielight.com/de//?p=12195 The Interest in Vielight’s Research Grows, but There is More…. International media has recently taken note of the work that Vielight is doing in Alzheimer’s Disease research. An article on Vielight’s work was published by a major UK newspaper, The Daily Telegraph. This article was picked up by a number of prominent newspapers. The list [...]

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The Interest in Vielight’s Research Grows, but There is More….

Vielight researchInternational media has recently taken note of the work that Vielight is doing in Alzheimer’s Disease research. An article on Vielight’s work was published by a major UK newspaper, The Daily Telegraph. This article was picked up by a number of prominent newspapers. The list of publications includes another leading UK newspaper, Daily News, and Canada’s own National Post, Calgary Herald, Ottawa citizen, Windsor Star, and more.

However, we are not all about Alzheimer’s. There are at least twenty projects on our research schedule, some in collaboration with major research centers. The more notable ones include a traumatic brain injury clinical trial, a study on cognition, meditation, study on blood viscosity, enhancement of sports performance, the mechanism of cellular signaling, EEG responses to various transductions, autism, and PTSD. Information on the published ones can be accessed on this Vielight webpage.

Vielight Scientists about Vielight Research

According to Dr. Genane Loheswaran, PhD., Research Manager at Vielight, “We have a busy but rewarding research program that keeps our team highly motivated, and in search of new discoveries. The idea of covering vast areas of brain conditions and functions may strike many scientists as being too ambitious. However, when one understands that photobiomodulation (PBM), delivered in the right way, is able to treat and affect the power sources of cells – mitochondria, the horizon of possibilities broadens significantly. With PBM, multiple benefits may be expressed, resulting in improvements in numerous functional outcomes.

In our research, using the Vielight Neuro Gamma and Alpha, we consistently observe quick and significant changes in the brain. We record and measure these changes with techniques such as EEG and neuropsychological assessments. The feedback from consumers of Vielight devices continues to surprise even the skeptics in us. It gives us great motivation to pursue new modalities to treat various brain conditions. We also have the unique and exciting opportunity to explore the extent to which we can uncover the potential of the human brain.”

Dr. Lew Lim, PhD., CEO of Vielight, added, “The results of these research efforts tend to lead us to develop even more devices that help people in specific and effective ways. This has always been our goal. With our engineering team in full swing, we hope to translate ideas to make practical and affordable devices. Because the devices are novel and the first of their kind, the challenges are numerous. The high levels of creativity and expertise of our engineering team make these new products a reality.”

Online forums on PBM and Vielight are Expanding

Vielight Facebook pageInterest in PBM is growing, and so are the online communities interested in this subject. Much of the discussion on PBM effect on the brain has been dominated by Vielight. This reflects the amount of innovation that stems from the Vielight team mission to improve the quality of lives through cutting-edge knowledge in the field.

Vielight has a Facebook page, where we share company events and the knowledge relevant to PBM and our research. There are also several independent Facebook groups that are great forums for independent sharing. The most relevant is the Vielight Knowledge Exchange Group. We are notably absent or infrequent in our participation for a couple of reasons. One, not to influence sharing of positive, as well as negative experiences. Another, we are not licensed to provide medical advice. Other active Facebook groups are Brain Photobiomodulation Exchange and Research, and Neuro-Photobiomodulation PEMF TDCS TMS.

Where to participate in Alzheimer’s Disease Clinical Trials

There are now two active sites recruiting participants for the Vielight RX Gamma Alzheimer’s Disease pivotal clinical trial. They are St. Michael’s Hospital, Toronto, and Bruyere Research Institute, Ottawa. In addition, the following sites will be opening soon: Progressive Medical Research, Port Orange, Florida, Healthtech Connex, Surrey, British Columbia, and Boston University School of Medicine. When new sites will be open for registration and recruitment, we will make announcements in our newsletter and social media. To enquire about participation in this trial, contact the managers for the trial, Applied Health Research Centre (AHRC) at St. Michael’s Hospital in Toronto.

Vielight welcomes Mingyang Chen, Quality and Product Engineer

Mingyang Chen joins Vielight as Quality and Product Engineer, bringing his expertise, which we need, as the company grows. Mingyang graduated from McGill University with a Masters’ degree in Materials Engineering. He will help us to meet our product quality goals and to improve trouble-shooting processes. He brings his experience in quality management, product development and software coding. Such continual strengthening of our team will help us to develop and release ground-breaking products that surprise with their practicality.

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Biohacking Extraordinary Brain Functions https://www.vielight.com/de/biohacking-extraordinary-brain-functions/?utm_source=rss&utm_medium=rss&utm_campaign=biohacking-extraordinary-brain-functions Fri, 08 Nov 2019 20:39:23 +0000 https://www.vielight.com/de//?p=10659 “Photo-Neuro-Hacking” is here! Vielight with its photobiomodulation (PBM) technology, has been the subject of growing interest in the field of biohacking of the brain. The delivery of light to influence brain functions is appealing to many biohackers. Not surprisingly, most are seeking ways to achieve that in an uncomplicated and affordable way, without the risk [...]

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“Photo-Neuro-Hacking” is here!

Vielight with its photobiomodulation (PBM) technology, has been the subject of growing interest in the field of biohacking of the brain. The delivery of light to influence brain functions is appealing to many biohackers. Not surprisingly, most are seeking ways to achieve that in an uncomplicated and affordable way, Vielight meditation biohackerswithout the risk of known side effects. For these reasons, Vielight’s method of delivering light to the brain in a non-invasive way is garnering great interest and support from clinicians, researchers and consumers. This is reflected in growing online and offline forums and discussions. The subjects of discussions and interest are the many possibilities of using Vielight devices for applications that have been considered difficult to achieve.

The recent Biohacker Summit 2019, held in Helsinki, Finland, on 1 and 2 of November 2019, manifested what excites biohackers. Notably, a big excitement was about the novel approach of the application and use of PBM by Vielight. Thus, the presence of Vielight among the exhibitors created a lively buzz in the air. Not surprisingly, there also was a very dynamic stream of visitors to our busy booth. Many visitors were turning up at the booth due to the word-of-mouth recommendations by users of Vielight devices. Interestingly, many visitors were meditators of various levels who were curious about improving their meditative experiences. As a result, the interest grew much bigger after the Vielight Founder & CEO, Dr. Lew Lim made a stage presentation entitled “Elevating Brain Performance with Light”.

How Photobiomodulation Influences Body and Brain Functions?

According to Dr. Lim, “Published research has shown that photobiomodulation (PBM) has clear influence on body and brain functions. The influence of PBM is significant – all the way from cell activity to high level performance outcomes. We continue to learn from these research results and extend the theories to their effects on humans by supporting clinical trials.

Evidently, biohackers now recognize that evidence clearly shows that the brain responds to PBM, if it is delivered to the brain in the right way. In this regard, we published data to show the effects of pulsing light of 40 Hz (Gamma), when it is applied to the brain. The light causes elevation of the power of alpha, beta and gamma oscillations and reduction of the power of the slow delta and theta. Alternatively, when we induce 10 Hz (Alpha) pulsation, significant response is largely observed in the alpha band. Overall, these findings show that the brain can respond differently to different pulse rates.biohacking brain functions

Consequently, Vielight has plans for further investigation in brain response. One day, we will be able to individualize intervention, so that the brain will be given the best boost for optimal function via PBM. Now, that would be a biohacker’s dream.”

 

Vielight Returns to TransTech 2019

The TransTech Conference 2019 will be held again on November 15-16, 2019 at Palo Alto, California. It is a conference where futuristic ideas in transformative technologies are exchanged. This is an area that Vielight identifies with. Dr. Lew Lim will be speaking on “Brain Photobiomodulation Advances”. He will update the attendees on the state of PBM as a brain stimulation and modulation method. Importantly, Vielight will also have a booth where attendees are welcome to visit and learn more about the Vielight devices. Furthermore, visitors will have the opportunity to speak with Vielight researchers, Dr. Alison Smith and Dr. Mahta Karimpoor, and experience the devices.

 

Vielight Makes its Presence in Europe at MEDICA

For the first time, Vielight will be exhibiting at the MEDICA Trade Show in Dusseldorf, Germany. The event will be held on November 18-21, 2019. Most notably, MEDICA is the largest medical product and services trade show in the world. This year more than 125,000 visitors and more than 5,000 exhibitors are expected. There has been a growing interest in Vielight devices in Europe. Thus, Vielight product experts, Gennady Lemud and Dominic Lim, are looking forward to introducing our products at the Vielight booth G40 at Hall 13.

 

Dr. Lew Lim to Speak in Perth, Western Australia

Dr. Lew Lim will be giving a talk in Perth, Australia at a special event, on November 26th 2019, from 11 am to 2 pm, at the Institute of Functional Neuroscience. His talk is titled “Photobiomodulation for Extraordinary Brain Functions”. Further information about the talk can be found at: https://www.facebook.com/events/1762789687199309/. Dr. Lim explains, “We are unearthing new information on how extraordinary brain functions can be achieved with light. I hope to share our experiences and research and to make this event a very rewarding one for attendees.”

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